• Content Approved Content Approved
  • Gluten Free Gluten Free
  • Suitable for Vegans Suitable for Vegans


de Mamiel First Fix Stress Response Serum
Free Gift



de Mamiel First Fix Stress Response Serum
Free Gift



Standard Delivery is FREE worldwide* Product code: SDX001

Content Approved

A serum that targets skin compromised by stress.

The de Mamiel First Fix is the result of 13 years' dedicated research and development, this ground-breaking response serum treats both the causes and symptoms of stress to leave skin feeling energized, healthy, and radiant.

Contains a host of effective and reparative plant actives and extracts, this powerful serum soothes, protects and repairs skin back to health.

Suitable for all skin types, including sensitive skin.



De Mamiel First Fix contains key ingredients: 

  • Ection - Supports a vulnerable barrier function and increases much-needed hydration.
  • Round-Headed Bush Clover - Injects skin with vitality and helps decrease the tell-tale signs of fatigue.
  • Passioline - An active clinically proven to support elastin and collagen synthesis for a firmer texture.
  • Telosense - Protects and enhances skin DNA health. 
  • Seabuckthorn Adaptogen - Boosts density and restores definition to skin that feels weakened.
  • Rhodiola Rosea - Promotes skin energy.
  • Blueberry Polyphenol - Soothes and brightens tone to reinstate skin's innate glow.
  • de Mamiel Cortisol Resilence Complex - An aromatherapeutic blend that includes Rose, Cape Chamomile, Vetiver and Sandalwood oils - which triggers a change in the way we respond to stress.

Sodium Hyaluronate, Squalane and quenching oils including Prickly Pear, Kahai and Pomegranate help reduce dryness, while Neurophroline helps to counteract the negative effects of cortisol to visibly improve skin tone.  

*89% of testers said their skin felt softer.
*80% of testers said their skin appeared more radiant.
*88% of testers said their skin felt smoother.

*According to consumer trials carried out by De Mamiel. 

Dermatologically tested & approved. Clinically tested.  

Made in the UK. Suitable for Vegans. Gluten-Free.

How To Use

Use every evening after cleansing & toning. Place 2-4 pumps in the palm of the hands, press together to warm, and activate the serum. Breathe the aroma in deeply, then massage over your face, working upward until everything is absorbed. 

Follow with your moisturiser and/or oil. 

If your skin is in need of intensive repair, use both morning and evening.


Aqua/Water/Eau, Glycerin, Propanediol, Camellia Japonica (tsubaki) seed oil, Kappaphycus alvarezii (red algae) extract, Caryodendron orinocense (kahai) nut oil, Ectoin, Opuntia ficus indica (prickly pear) seed oil, Squalane, Helianthus annuus (sunflower) seed oil, Diheptyl succinate, Capryloyl Glycerin/Sebacic Acid Copolymer, Passiflora edulis (maracuja) seed oil, Punica granatum (pomegranate) seed oil, Cetearyl alcohol, Cetyl phosphate, L-Arginine, Benzyl alcohol, Curcuma longa (turmeric) Callus Lysate, Lespedeza capitata (roundhead bush clover) leaf/stem extract, Sodium hyaluronate, Maltodextrin, Salicylic acid, Lysolecithin, Sclerotium Gum, Tocopherol (Vitamin e), Vaccinium angustifolium (blueberry) Fruit Extract, Xanthan Gum, Parfum (Fragrance)**, Tephrosia purpurea (wild indigo) seed extract, Rhodiola Rosea (rhodiola) root extract, Vetiveria zizanoides (vetiver) root oil*, Hippophae rhamnoides (seabuckthorn) kernel extract, Pelargonium graveolens (rose geranium) leaf oil*, Santalum album (sandalwood) wood oil, Pullulan, Simmondsia chinensis (jojoba) seed oil*, Sorbic acid, Eriocephalus punctulatus (cape chamomile) flower oil*, Citric acid, Rosmarinus Officinalis (Rosemary) Leaf Extract, Sodium Benzoate, Hydrolyzed Soy Protein, Hydrolyzed Yeast Protein, Linalool˚, Citronellol˚, Geraniol˚, Citral˚ 

˚Natural essential oil constituents   


Flower and gem essences of Black-eyed Susan, Bush Fuchsia, Crowea, Jacaranda, Little Flannel Flower, Grey Spider Flower, Obsidian.

Delivery & Returns

We offer FREE UK delivery on all orders over £25 & FREE international delivery on all orders over £50 up to 2kgs.

All available delivery options will be listed at checkout or find more delivery options (including Next Day & Saturday delivery) HERE 

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